HDBIG-SCCA is an HDBIG toolkit focusing on Sparse Canonical Correlation Analysis (SCCA). The current version includes matlab implementation of knowledge guided SCCA model (KG-SCCA). It can be applied to examine the association between genetic variations and imaging phenotypes.

HDBIG-SCCA v1.0.0 is released: Download, Documentation (PDF)


Yan J, Du L, Kim S, Risacher SL, Huang H, Moore JH, Saykin AJ, Shen L, for the ADNI (2014) Transcriptome-guided amyloid imaging genetic analysis via a novel structured sparse learning algorithm. Bioinformatics, Vol. 30 ECCB 2014, pages i564–i571.